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  • Title: [Growth inhibition by antibiotics and the production of resistance to them in a population of Nostoc linckia].
    Author: Ahmad MH.
    Journal: Mikrobiologiia; 1975; 44(5):870-3. PubMed ID: 813088.
    Abstract:
    Increasing concentrations of penicillin and streptomycin inhibited the growth of the blue-green alga Nostoc linckia. Although the alga could build up resistance to higher concentrations of penicillin (1000 mcg/ml), it was very sensitive to streptomycin beyond a concentration of 0.02 mcg/ml. Two stable mutants, one resistant to 1000 mcg penicillin/ml and another to 0.02 mcg streptomycin/ml were isolated, of which the latter had lost its nitrogen fixing capacity. Drug resistance seems to be due to nuclear or gene mutation.
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