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  • Title: Liposomal amphotericin-B (AmBisome) for treatment of cutaneous widespread candidosis in an infant with methylmalonic acidaemia.
    Author: Stöckler S, Lackner H, Ginter G, Schwinger W, Plecko B, Müller W.
    Journal: Eur J Pediatr; 1993 Dec; 152(12):981-3. PubMed ID: 8131816.
    Abstract:
    In a 10-week-old infant with vitamin B12-unresponsive methylmalonic acidaemia, cutaneous candidosis (Candida albicans) progressed rapidly despite topical antifungal treatment. After 1 week of intravenous therapy with liposomal amphotericin-B (AmBisome) the dermatitis disappeared completely and blood cultures were sterile. No side-effects were observed. This is one of the first experiences in the treatment of infants with this new antifungal agent.
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