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Title: New structures and bioactivity patterns of bengazole alkaloids from a choristid marine sponge. Author: Rodríguez J, Nieto RM, Crews P. Journal: J Nat Prod; 1993 Dec; 56(12):2034-40. PubMed ID: 8133293. Abstract: New bengazoles 3-9 as inseparable mixtures are reported from the sponge Jaspis cf. coricea collected in Papua New Guinea. These compounds contain a new variation of the unusual bisoxazole core present in bengazole A [1]. The B-ring oxazole hexatetraol side chain is varyingly substituted with either myristic acid or 13-methylmyristic acid. Hydrolysis of three different bengazole mixtures each yielded an identical tetraol, bengazole Z [11].[Abstract] [Full Text] [Related] [New Search]