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  • Title: [Carbamazepine poisoning: protracted course with development of intestinal atony and hepatic toxicity].
    Author: Baischer W, Wagner A, Seidler D, Musalek M, Laggner A.
    Journal: Wien Klin Wochenschr; 1994; 106(1):27-9. PubMed ID: 8135028.
    Abstract:
    A 43 year-old female patient with a history of manic-depressive illness and prophylactic carbamazepine (CBZ) medication ingested a potentially lethal overdose of 20 g of the substance. Neurotoxic symptoms reached full intensity after about 24 hours. Subsequently, the patient developed a gastrointestinal atony, which proved to be refractory to treatment for several days. Moreover, there was an increase of bilirubin. Parallel to this we observed the persistence-and even intermittent re-increase--of toxic serum CBZ concentrations for one week with corresponding protracted clinical symptomatology.
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