These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Asymmetrical lipid charge changes the subconducting state of the potassium channel from sarcoplasmic reticulum.
    Author: Anzai K, Takano C, Tanaka K, Kirino Y.
    Journal: Biochem Biophys Res Commun; 1994 Mar 15; 199(2):1081-7. PubMed ID: 8135782.
    Abstract:
    The K+ channel of sarcoplasmic reticulum was incorporated into planar lipid bilayers having various net surface charges. The conductance of both the main-state and substate increased with the increase in negative charges of the membrane and vice versa. The change in the conductance of the substate was larger than that of the main-state. The K+ channel reconstituted into asymmetrical planar lipid bilayers revealed that the effect on the substate was derived from only one half (trans) of the bilayer. The substate of the K+ channel may assume a conformation in which part of the channel located at the trans side is susceptible to some changes induced by the trans surface charge.
    [Abstract] [Full Text] [Related] [New Search]