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Title: Localization of disulfide bridges and free sulfhydryl groups in human eosinophil granule major basic protein. Author: Oxvig C, Gleich GJ, Sottrup-Jensen L. Journal: FEBS Lett; 1994 Mar 21; 341(2-3):213-7. PubMed ID: 8137941. Abstract: Eosinophil granule major basic protein (117 residues) is known to contain free sulfhydryl groups. Here we have located in the amino acid sequence the half-cystine residues present as cysteine, and identified those engaged in disulfide bridges. Of the 9 half-cystine residues, 5 are unpaired cysteines (Cys2, Cys23, Cys42, Cys64, and Cys96), while 4 form disulfides (Cys20-Cys115, and Cys92-Cys107).[Abstract] [Full Text] [Related] [New Search]