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  • Title: Grasp reflex strength from right and left hands is associated with pH stressor from the umbilical arterial blood in human newborns: handedness and sex-related differences.
    Author: Tan U, Zor N, Kücüközkan T, Akcay F, Yigitoglu R, Bakan E, Kutlu N.
    Journal: Int J Neurosci; 1993 Oct; 72(3-4):149-56. PubMed ID: 8138371.
    Abstract:
    Grasp reflex and its asymmetry was studied in relation to pH of the umbilical blood in human newborns, to examine whether the degree of acidity in fetal blood (birth stress) is associated with cerebral laterality. Low pH values were considered as an index for birth stress. Grasp-reflex strength was found to be directly related to pH in total sample. There were sex-related differences. Namely, this correlation was true only for female newborns, not for males. Right minus left grasp-reflex strength linearly increased with pH, i.e., low pH values were associated with left-hand dominance, but only in males. The grasp-reflex asymmetry was not related to pH in females. It was concluded that blood pH may be associated with motor asymmetry and motor development in human newborns, but show sex-related differences; female brain seemed to be more sensitive to pH changes than male brain. The results partly supported the Bakan's hypothesis that birth stress may be associated with left-handedness.
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