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  • Title: Role of the beta-amyloid precursor protein in Alzheimer's disease.
    Author: Ashall F, Goate AM.
    Journal: Trends Biochem Sci; 1994 Jan; 19(1):42-6. PubMed ID: 8140621.
    Abstract:
    Deposition of beta-amyloid peptide in the brain is an early event in Alzheimer's disease, the most common cause of dementia. Studies of the beta-amyloid precursor protein (APP), which gives rise to beta-amyloid, are rapidly leading to a better understanding of the biochemical basis of the disease--a prerequisite for rational drug development.
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