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  • Title: Synthesis and antiviral activity of some new benzofuran derivatives.
    Author: Papadaki-Valiraki A, Todoulou O, Filippatos E, Tsotinis A, Ikeda S, De Clercq E.
    Journal: Arzneimittelforschung; 1993 Dec; 43(12):1363-6. PubMed ID: 8141829.
    Abstract:
    New derivatives of benzofuran were prepared and evaluated for their in vitro activity against a number of DNA and RNA viruses in various cell systems. Compounds 1-(7-dodecyloxy-2-benzofuranyl)ethanone (3c) and 1-(7-tridecyloxy-2-benzofuranyl)ethanone (3d) exhibited a specific activity against respiratory syncytial virus in HeLa and compound [di(2-acetylbenzofuranyl-7-oxy)]-n-propane (5a) against influenza A virus in MDCK.
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