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  • Title: HLA antigens in Arab children with steroid-responsive nephrotic syndrome.
    Author: Zaki M, Daoud AS, al Saleh QA, al Najedi AK, White AG.
    Journal: Pediatr Nephrol; 1994 Feb; 8(1):74-5. PubMed ID: 8142232.
    Abstract:
    Forty-eight Arab patients with steroid-responsive childhood nephrotic syndrome were studied for the frequency of HLA-A, -B, -C and -DR antigens. HLA-DR7 was significantly increased in the patient group (63% vs. 28%, P = 0.0002) confirming reports of a DR7 association in other ethnic groups and indicating a universal association with this antigen. HLA-CW6 was also significantly increased (44% vs. 21%, P corr. = 0.042). HLA-DQW1 was significantly reduced in the patients (29% vs. 57%, P corr. = 0.012) as was HLA-CW4 (6% vs. 24%, P corr. = 0.042).
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