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  • Title: [Multiple antibiotic resistance in Haemophilus influenzae related to serogroup B].
    Author: Campos J, Seuba T, Trujillo G, Rodríguez A, Roca J.
    Journal: Enferm Infecc Microbiol Clin; 1993 Dec; 11(10):552-4. PubMed ID: 8142505.
    Abstract:
    AIM: To study the association between multiply antibiotic resistance in Haemophilus influenzae and H. influenzae type B, and to describe levels and patterns of antibiotic resistance. METHODS: Statistical analysis and susceptibility of 231 H. influenzae strains (52 type B and 179 non-typable ) isolated consecutively from pediatric patients. RESULTS: Resistance levels for type B and non-typable strains were: Ampicillin, 55.3% vs 28.8%; Chloramphenicol, 44.7% vs 9.2%; Ampicillin plus chloramphenicol, 40.4% vs 7.6%; cotrimoxazole, 89.3% vs 67.4%; resistance to six or more antibiotics, 36.0% vs 3.8%. CONCLUSION: Multiply antibiotic resistance in H. influenzae is strongly associated with type B strains, with age of 4 or younger, and with isolation from CSF or blood. Resistance is sustained over long periods of time.
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