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  • Title: [Successful combination therapy in bronchial asthma. Anti-obstructive and anti-inflammatory treatment].
    Author: Thomsen M, Zahn T.
    Journal: Fortschr Med; 1994 Jan 20; 112(1-2):39-42. PubMed ID: 8144119.
    Abstract:
    METHOD: In a post-marketing surveillance study, patient data were documented with the aim of assessing the effect of a combination of both anti-inflammatory and bronchodilatory treatment with inhaled beclomethasone dipropionate and a sustained-release theophylline preparation. A total of 2,166 patients with mild-to-moderate bronchial asthma (FEV1 about 60%) were included in the multicenter open study. RESULTS: It was found that treatment with inhaled glucocorticoid and sustained-release theophylline resulted in a clear improvement in symptom scores. More than 90% of the physicians and patients rated the treatment "very good" or "good". Only 4.6% of the participants had side effects. CONCLUSION: It may be concluded that combination therapy with inhaled glucocorticoid and sustained release theophylline is a safe and effective form of treatment of mild-to-moderate asthma.
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