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  • Title: Antitussive effects of levodropropizine in the dog.
    Author: Munt PL, Clavenna G, Algate DR, Leach RM.
    Journal: Arzneimittelforschung; 1994 Feb; 44(2):153-5. PubMed ID: 8147948.
    Abstract:
    The antitussive activity of levodropropizine (S(-)3-(4-phenyl-piperazine-1-yl)-propane-1,2-diol, DF 526, CAS 99291-25-5) was evaluated after oral administration to the conscious dog. Levodropropizine had a good antitussive activity, comparable with, but having a longer duration of action than dropropizine, the racemate from which it is derived. The antitussive activity of levodropropizine in the dog was approximately 1/20 of that of codeine phosphate.
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