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  • Title: Rapidly fatal necrotising fasciitis caused by Streptococcus pyogenes.
    Author: Donaldson PM, Naylor B, Lowe JW, Gouldesbrough DR.
    Journal: J Clin Pathol; 1993 Jul; 46(7):617-20. PubMed ID: 8157746.
    Abstract:
    AIMS: To describe the morbid anatomical and bacteriological features in a series of five cases of rapidly fatal Streptococcus pyogenes necrotising fasciitis. METHODS: Post mortem and bacteriological examinations were made of five patients dying within 48 hours from rapidly fatal necrotising fasciitis. RESULTS: All five cases died rapidly from a toxic Streptococcus toxin syndrome as a result of developing necrotising fasciitis following trivial injury. CONCLUSIONS: Necrotising fasciitis caused by Streptococcus pyogenes infection can be rapidly fatal. This is probably the result of a toxic shock syndrome. Rapid, early diagnosis and swift and probably empirical treatment is required to avoid a fatal outcome.
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