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  • Title: [Intravascular thrombolytic therapy in the treatment of acute thrombophlebitis of the lower extremities and pelvis (Report 1)].
    Author: Gervaziev VB, Karpenko AA, Chernenko VF.
    Journal: Khirurgiia (Mosk); 1993 Dec; (12):16-23. PubMed ID: 8158943.
    Abstract:
    A new method of thrombolytic therapy is described and substantiated. It consists in percutaneous catheterization of the popliteal vein with a system of paired catheters with the inner one being advanced during infusion of the thrombolytics in the thickness of the thrombus along the length of the proximal segments of the main vein. Phlebographic control is accomplished through the outer, short catheter. The preparations of streptokinase awelysin and celiase were used. The new method of treatment was applied in 27 cases. Comparison with groups of patients treated by other methods of systemic and regional thrombolytic therapy showed that the efficacy of the suggested method was higher. Good late results were found in 72% of patients of the main group. A necessary condition of the applied method is prevention of thromboembolism of the pulmonary arteries by temporary implantation of a cava-filter into the inferior vena cava.
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