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  • Title: [Hydantoin fetal syndrome].
    Author: Dang PM, Dufetelle B, Bonnetblanc JM.
    Journal: Ann Dermatol Venereol; 1993; 120(9):621-4. PubMed ID: 8161117.
    Abstract:
    We report a case of distal finger hypoplasia associated with foetal hydantoin syndrome (FHS). The occurrence of this syndrome is thought to be due to abnormalities of collagen, cytochrome P 450 and arachidonic acid metabolism. The risk of developing FHS could be evaluated by counting the glucocorticoid receptors of lymphocytes or by measuring epoxide hydrolase activity through amniocentesis. FHS can be prevented by taking folates during pregnancy.
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