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Title: Organization and function of the cytoskeleton in polarized epithelial cells: a component of the protein sorting machinery. Author: Mays RW, Beck KA, Nelson WJ. Journal: Curr Opin Cell Biol; 1994 Feb; 6(1):16-24. PubMed ID: 8167021. Abstract: Development and maintenance of cell-surface polarity in epithelial cells requires specialized localization of proteins to functionally and structurally distinct plasma membrane domains. The organization of these domains is dependent upon targeted delivery of transport vesicles between different membrane compartments, and upon protein sorting in the membranes of the Golgi complex and cell surface. Increasing evidence has been gathered in recent years that cytoskeletal components facilitate these processes.[Abstract] [Full Text] [Related] [New Search]