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  • Title: An immunohistochemical study of Langerhans cells, T-cells and the HLA antigen in human cornea.
    Author: Li Q, He Y.
    Journal: Yan Ke Xue Bao; 1993 Sep; 9(3):121-5. PubMed ID: 8168605.
    Abstract:
    The distribution of Langerhans cells (LC), T-cell subsets and HLA antigen in 12 normal and 7 morbid corneas, including 4 of suppurative corneal ulcer and 3 of uveogenic endophthalmitis, was investigated with monoclonal antibodies. The results revealed that a small amount of LC and T-cell subsets were present in the limbal region of normal corneas, while large numbers of LC and OKT4+ were observed in the corneas of suppurative ulcer. HLA-A, B, C antigens were expressed on the epithelial cells and keratocytes of the normal corneas, while the HLA-DR antigens were expressed on the surface of LC at the limbus.
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