These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Double-labeling of experimental acute myocardial infarcts with 113mIn- and 99mTc-EDTMP.
    Author: Holman BL, Jones AG, Davis MA, Askenazi J, Maroko PR.
    Journal: J Nucl Med; 1976 Jun; 17(6):508-11. PubMed ID: 817000.
    Abstract:
    The feasibility of double-labeling of acute myocardial infarcts with 113mIn-EDTMP [ethylenediaminetetra(methylene phosphonic acid)] and 99mTc-EDTMP was evaluated. The in vitro distributions of these tracers in acute myocardial infarcts in dogs and their selectivities for infarcted versus noninfarcted myocardium were compared. Both tracers concentrated in acutely infarcted myocardium, and there was excellent correlation between their uptakes (r = 0.88). They also provided complete separation between infarcted and uninfarcted tissue, as checked by histology. Accordingly, these agents show promise for the multiple-labeling of acute myocardial infarcts in experiments to determine the natural course of myocardial infarction and the efficacy of therapy aimed at limiting infarct size. In addition, 113mIn-EDTMP may be useful for serial scintigraphy during the early phase of acute myocardial infarction when the damage may be, at least to some extent, reversible.
    [Abstract] [Full Text] [Related] [New Search]