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  • Title: Measurement of dead-space in a model lung using an oscillating inspired argon signal.
    Author: Williams EM, Gavaghan DJ, Oakley PA, Sainsbury MC, Xiong L, Black AM, Hahn CE.
    Journal: Acta Anaesthesiol Scand; 1994 Feb; 38(2):126-9. PubMed ID: 8171946.
    Abstract:
    In a model lung, airways dead-space can be accurately measured using a forced inspired oscillating argon signal, which varies sinusoidally about a mean concentration of 6% v/v with an amplitude of +/- 4% v/v. With sinusoid forcing periods longer than 120 seconds, and at a breathing rate of 13.4 breaths minute-1, the mean airways dead-space can be measured with a standard error of less than 5%. Sinusoid forcing periods shorter than 120 s provided inaccurate estimates of dead-space and so should not be used with this technique.
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