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  • Title: [The effect of different types of premedication on gastric juice volume and pH].
    Author: Radev RN.
    Journal: Akush Ginekol (Sofiia); 1993; 32(1):17-20. PubMed ID: 8172338.
    Abstract:
    60 pregnant women and 60 parturients treated with selected surgery were studied according to the influence of different types premedication on the gastric juice volume and pH. Parturients were divided into six groups (AI-AVI) with 10 participants in each one. Groups were comparable for a variety of signs-age, type and duration of the surgical procedure and methods of carrying out the general anaesthesia. Surgically treated patients were also divided into six groups (from B 1 to B), each group containing ten patients with similar symptoms. This makes possible comparison between them. Parturients from group AI were given each 0.007 mg/kg/body weight atropine i.v. 20 min before introduction in anaesthesia; group A II-0.014 mg/kg/body weight metacin; group AIII-0.3 mg/kg/body weight alkosin; group AIV-o.014 mg/kg/body weight metacin and 0.21 mg/kg/body weight dimidrol. Parturients from AV were given each two measure spoons Almagel A per os-an antacid drug-30 min before introduction in anesthesia and 0.007 mg/kg/body weight atropine i.v., introduced 20 min before the beginning of anesthesia. The parturients from group AVI were given each 400 mg H2 blocker (2 tabl.) per os-cimetidine-2 hours before the beginning of anesthesia and atropine 20 min before introduction in anesthesia in the same dosage as for the parturients from group AV. Surgically treated patients from group BI received as a premedication the following drugs 20 min before the beginning of anesthesia: atropine-0.007 mg/kg/body weight, fentanyl-0.001 and droperidol-0.03 mg/kg/body weight introduced i.v. Group BII-geluzil liquid-2 tea spoons 30 min before introduction in anesthesia and atropine i.v. 20 min at the beginning of anesthesia; group BIII received as a premedication dormicum-0.1 mg/kg/body weight and atropine in the same dosage as for the patients from group BII. Group BIV received as a premedication 20 ml 8.4% solution of sodium bicarbonate per os 20 min before the beginning of anesthesia and atropine in the same dosage as the patients from group BIII; BV received 0.003 mg/kg/body weight gastrodin, introduced i.v. 20 min before the beginning of anesthesia. Patients from group BVI received as a premedication for 2 hours before the beginning of anesthesia gastrozepin 2 tabl. (50 mg) per os and atropine in the same dosage as the patients from group BII. Gastric juice was taken by means of nasogastric tubing immediately before premedication, introduction in anesthesia and its end to fix its pH. The volume of gastric juice generated during the surgical procedure was determined before extubation.(ABSTRACT TRUNCATED AT 250 WORDS)
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