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  • Title: Limitations of diazoxide reversal of vasospasm.
    Author: Heros RC, Lavyne MH, Zervas NT.
    Journal: Stroke; 1976; 7(2):118-20. PubMed ID: 817424.
    Abstract:
    Diazoxide failed to safely relieve cerebral vasospasm by intracisternal injections in dogs and by intracarotid injections in monkeys despite in vitro documentation of arterial relaxation with this agent. Administration of the drug frequently produced hypotension and, in the presence of vasospasm, was associated with a high mortality rate.
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