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  • Title: [The morphological and immunohistochemical study of esophageal pseudosarcomatous and carcinosarcomas--report of 10 cases].
    Author: Zhang X.
    Journal: Zhonghua Zhong Liu Za Zhi; 1993 Sep; 15(5):355-7. PubMed ID: 8174480.
    Abstract:
    Twenty cases of esophageal carcinosarcoma were diagnosed and treated in this hospital during 1958-1990. Of which, 10 cases were reexamined by morphology and immunohistochemistry stained with 17 different antibodies. The results showed that: (1) There were 6 cases of true carcinosarcoma, 3 of pseudosarcoma and 1 case belonging to primary esophageal malignant fibrohistiocytoma; (2) In the cases of true carcinosarcoma, the tumor tissue displayed certain heterogeneity of carcinomatous and/or sarcomatous components, suggesting a potential for multi-directional differentiation; (3) It may be important that most of the tumors showed an intra-luminal or polypoid growth pattern and fewer metastasis, with a better prognosis. There are 6 surviving cases among 9 followed up over 2 years and the longest survivor has been up to 15 years.
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