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  • Title: Prevention of anaphylactic-anaphylactoid reactions to anesthetics in high-risk allergic patients.
    Author: Lorenzi P, Marsili M, Manetta G, Linden M, Boncinelli S.
    Journal: Anesth Pain Control Dent; 1993; 2(4):227-32. PubMed ID: 8180526.
    Abstract:
    To confirm the role of preventive procedures in high-risk allergic patients, immunological tests in vivo for anesthetics were carried out in 251 atopic patients. The 6-month follow-up showed a complete absence of adverse reactions during the clinical use of hypnotic and muscle relaxant drugs. In the case of local anesthetics, five adverse reactions were observed after dental treatment--four were related to a psychogenic mechanism, and one could not be clearly linked to the local anesthetic. It is possible to confirm that the use of a tested drug that yields negative results has a lower probability of inducing anaphylactic-anaphylactoid reactions during anesthesia.
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