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  • Title: Production of enterotoxin, verotoxin, hemolysin and cytotoxic necrotizing factor by Escherichia coli of intestinal and extraintestinal origin.
    Author: Hostacká A.
    Journal: Folia Microbiol (Praha); 1994; 39(1):79-82. PubMed ID: 8181786.
    Abstract:
    Seventy-six Escherichia coli strains were examined for heat-labile enterotoxin (LT), verotoxin (VT), hemolysin (HLy) and cytotoxic necrotizing factor (CNF). Thirty-six strains were isolated from patients suffering from diarrhea and forty from different extraintestinal infections. The number of LT-producing strains was low (2.6%) (one of intestinal and one of extraintestinal origin). Verotoxin was produced only by one extraintestinal strain. Four intestinal strains were hemolytic (11.2%) and also positive for CNF. From 24 hemolytic strains of extraintestinal origin (60%), 17 produced also CNF. Most of the hemolytic (30%) as well as CNF-producing strains (22.5%) were isolated from urine. Our results are similar to those of other studies confirming the close association between hemolysin and CNF production as well as a possible role of these toxic factors in pathogenesis of extraintestinal infections caused by E. coli.
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