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  • Title: A chronic implant for intracerebral mass spectrometric gasometry in the rhesus monkey.
    Author: Kennealy JA, Brown RD, Karl AA, Hogue FW, Buehring WJ.
    Journal: Lab Anim Sci; 1976 Apr; 26(2 Pt l):230-3. PubMed ID: 818447.
    Abstract:
    A cranial implant was developed to facilitate mass spectrometric gasometry in cerebral tissue of conscious primates. It is permanently fixed to the skull and allows repeated introduction of a Teflon diffusion membrane into the cerebrum. The implant is simple to manufacture and mount. It has been tolerated well with repeated introduction of the catheter for more than 6 mo in 10 rhesus monkeys. The preparation avoids the complication and artifacts of an acute surgical preparation for investigation of cerebral pO2 and CO2.
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