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  • Title: Cardiac paraprotein associated with Waldenstrom's macroglobulinemia: a case report.
    Author: Yowell RL, Hammond EH.
    Journal: Ultrastruct Pathol; 1994; 18(1-2):229-32. PubMed ID: 8191631.
    Abstract:
    A case of myocardial paraprotein deposition in a patient with Waldenstrom's macroglobulinemia is presented. Routine light microscopy revealed diffuse widening of interstitial regions by pale eosinophilic material that had a grayish cast on trichrome stains and was Congo red negative. Immunofluorescence showed strong immunoglobulin M and kappa light chain staining around blood vessels but predominantly around myocytes. Ultrastructural examination revealed massive deposition of flocculent electron-dense material around myocytes and occasionally around blood vessels.
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