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  • Title: [The production of IL-1, IL-3 and CSA by bone marrow nuclear elements during the recovery of bone marrow hematopoiesis after lethal irradiation and the transplantation of syngeneic bone marrow].
    Author: Dygaĭ AM, Buznik DV, Bogdashin IV, Agafonov VI.
    Journal: Radiats Biol Radioecol; 1994; 34(2):220-4. PubMed ID: 8193711.
    Abstract:
    The production of haemopoietic factors (IL-1, IL-3, CSA) by adherent and nonadherent cells of lethally irradiated CBA mice bone marrow and after syngenic myelokaryocyte transplantation was studied. Radioresistant myelokaryocytes capable to produce haemopoietic factors IL-1, CSA as early as 24 hr after irradiation were found in adherent cell fraction. The synthesis of humoral factors (IL-3, CSA) by nonadherent bone marrow elements was realised in a late terms of experiment (3-6 days) that was connected with forming of functionally valuable cell forms from transplanted or viable stem cells.
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