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  • Title: Antitumor-promoting activity of mallotojaponin, a major constituent of pericarps of Mallotus japonicus.
    Author: Satomi Y, Arisawa M, Nishino H, Iwashima A.
    Journal: Oncology; 1994; 51(3):215-9. PubMed ID: 8196903.
    Abstract:
    Mallotojaponin, a major constituent of the pericarps of Mallotus japonicus (Euphorbiaceae), inhibited the action of tumor promoter in vitro and in vivo; it inhibited tumor promoter-enhanced phospholipid metabolism in cultured cells, and also suppressed the promoting effect of 12-O-tetradecanoylphorbol-13-acetate on skin tumor formation in mice initiated with 7,12-dimethylbenz-[a]anthracene.
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