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  • Title: Collagenous colitis and lymphocytic colitis.
    Author: Zeroogian JM, Chopra S.
    Journal: Annu Rev Med; 1994; 45():105-18. PubMed ID: 8198370.
    Abstract:
    Collagenous and lymphocytic colitis are newly recognized causes of chronic watery diarrhea that typically affect middle-aged patients. Although endoscopic studies are normal, inflammatory changes and (in the case of collagenous colitis) collagen deposition occur histologically in the colonic mucosa. The pathogenesis of these disorders remains a mystery, but the possible causes are intriguing. Patients may experience spontaneous remissions and relapses, but treatment with sulfasalazine or prednisone is usually effective for patients with distressing symptoms.
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