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  • Title: Ectopic human chorionic gonadotrophin (HCG) production: is the detection by serum analysis of HCG of clinical relevance in transitional cell carcinoma of the bladder?
    Author: Smith DJ, Evans HJ, Newman J, Chapple CR.
    Journal: Br J Urol; 1994 Apr; 73(4):409-12. PubMed ID: 8199829.
    Abstract:
    OBJECTIVE: To assess the potential value of ectopic beta-human chorionic gonadotrophin (beta HCG) measurement in the clinical management of transitional cell carcinoma (TCC). PATIENTS AND METHODS: A prospective serological study of 163 consecutive patients undergoing cystoscopy as new or review cases was performed to assess any correlation between beta HCG production and histological grading or stage. RESULTS: Ten per cent of patients with TCC had a raised beta HCG level but there was no correlation with tumour differentiation, staging or prognosis. CONCLUSIONS: beta HCG has no role as a tumour marker for TCC and therefore appears unlikely to play a part in the clinical management or treatment of urothelial tumours.
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