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  • Title: [Intracavernous auto-injection of prostaglandin E1 for diagnosis and treatment of erectile dysfunction].
    Author: Arielly J, Weinberg D, Eliraz A, Adam M, el-Hanani BI, Eisenkraft S.
    Journal: Harefuah; 1994 Apr 01; 126(7):369-73, 426. PubMed ID: 8200581.
    Abstract:
    34 impotent patients were offered auto-injection therapy and all except 2 began treatment. Prostaglandin E1 (PGE) was used regularly for a mean of 8.6 months (range 1-17). The onset of erection was 5-30 min (mean 11.4) after injection and it lasted at least 30 min (mean 106.2 min). An erection of more than 6 hrs was observed in only 2 patients. There have been no instances of cavernous fibrosis, chemical priapism or systemic reactions. The most common adverse effect was penile pain after injection. It was mild to moderate in 4 patients (11.7%), and in only 1 was it severe enough to require stopping treatment. Overall, intracavernous injection of PGE appears to be safe, effective treatment for impotence without side-effects other than pain after injection in a few.
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