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  • Title: Effects of piracetam on erythropoiesis and leukopoiesis in rats.
    Author: Nyagolov Y, Dyankov E, Ganchev T.
    Journal: Acta Physiol Pharmacol Bulg; 1993; 19(4):97-100. PubMed ID: 8203283.
    Abstract:
    Erythro- and leukopoiesis in rats after 10-day treatment with piracetam (2 x 200 mg/kg b.w.) were studied. Increase of reticulocytes and of 59-iron incorporation in newly formed erythrocytes accompanied by an increase of the index of maturation of erythroblasts in bone marrow were found suggesting a piracetam-induced stimulation of erythropoiesis. Piracetam also increased the number of small lymphocytes and the maturation of granulocytes in bone marrow. It is supposed that piracetam exerting a positive effect on the metabolic processes of erythroid, myeloid and lymphoid precursors stimulates their proliferation and differentiation.
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