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  • Title: The major histocompatibility complex in man.
    Author: Buc M.
    Journal: Folia Biol (Praha); 1993; 39(5):223-42. PubMed ID: 8206168.
    Abstract:
    The HLA system is a complex of polymorphic genes divided into a class I group and a class II group. The disclosed tertiary structure of HLA antigens indicates that they are principally involved in binding a variety of self and foreign immunogenic peptides and in their presentation to T cells. Class III HLA region is located between class I and class II regions. It comprises many genes, some of them participate in events of the immune response, too.
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