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  • Title: Bleach use and HIV seroconversion among New York City injection drug users.
    Author: Titus S, Marmor M, Des Jarlais D, Kim M, Wolfe H, Beatrice S.
    Journal: J Acquir Immune Defic Syndr (1988); 1994 Jul; 7(7):700-4. PubMed ID: 8207647.
    Abstract:
    We employed a nested case-control study design to evaluate the efficacy of bleach-cleaning of needles and syringes among injecting drug users (IDUs) as a means of preventing human immunodeficiency virus (HIV) infection. Sixteen HIV-seroconverters who responded to bleach use questions and who reported injecting with shared or used equipment in the 6 months prior to their first positive visit were compared with 89 controls. Controls had remained HIV-seronegative at two or more visits, reported injecting with shared or used equipment, responded to bleach-cleaning questions, and were seen at recall visits +/- 6 months from the date of seroconversion of the index case. Risk factors associated with HIV seroconversion in univariate analyses were a history of sexual intercourse with an HIV-infected partner and the frequency of speedball (mixed heroin and cocaine) injections. After adjusting for confounders, we found no evidence that bleach use protected against HIV infection.
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