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  • Title: Tumor cytotoxicity and production of interleukin-1 and tumor necrosis factor from blood monocytes of cervical carcinoma patients.
    Author: Nadkarni JJ, De AK, Jhaver KJ, Kamat MR.
    Journal: Neoplasma; 1994; 41(2):123-8. PubMed ID: 8208316.
    Abstract:
    To assess the functional integrity of monocytes in patients with cervical carcinoma, cytotoxic potential of peripheral blood monocytes and their ability to secrete interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha) after activation with different stimulating agents were studied. Comparable levels of monocyte-mediated cytotoxicity were observed in healthy donors and patients. The production of IL-1 and TNF-alpha by monocytes of healthy donors and patients was similar indicating no defect in monocyte functions in these patients.
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