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  • Title: Prevalence of isolated urethral asymptomatic Chlamydia trachomatis infection in the absence of cervical infection in incarcerated adolescent girls.
    Author: Morris RE, Legault J, Baker C.
    Journal: Sex Transm Dis; 1993; 20(4):198-200. PubMed ID: 8211536.
    Abstract:
    BACKGROUND AND OBJECTIVES: Adolescent girls may have isolated asymptomatic urethral Chlamydia trachomatis infection. GOAL OF THIS STUDY: To determine if a single direct fluorescent antibody (DFA) slide can detect as many urethral and cervical infections as the use of separate slides and to determine if isolated urethral infection occurs. STUDY DESIGN: During pelvic examinations upon admission, DFA slides were prepared from the cervix, from the urethra, and with cells from both sites. RESULTS: Of 125 girls, 17 had C. trachomatis infection: 4 in the urethra only (24%), 5 in the cervical sample only (31%), 5 in both sites (31%), 3 had positive results only on the combined slide, and 1 had a positive result on the cervical slide and an inadequate urethral slide. CONCLUSION: Isolated urethral C. trachomatis infection occurs frequently, and sampling both sites as opposed to sampling the cervix alone increases the number of cases found by 24% (P < 0.002). Using a single slide to detect infection in both sites detects as many infections as using two separate slides.
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