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  • Title: Primary rhabdomyosarcoma of the iliac bone in an adult: a case mimicking fibrosarcoma.
    Author: Oda Y, Tsuneyoshi M, Hashimoto H, Iwashita T, Ushijima M, Masuda S, Iwamoto Y, Sugioka Y.
    Journal: Virchows Arch A Pathol Anat Histopathol; 1993; 423(1):65-9. PubMed ID: 8212536.
    Abstract:
    Primary rhabdomyosarcoma of bone is exceedingly rare. We present a case of rhabdomyosarcoma of the iliac bone in a 32-year-old male. Histologically, the tumour consisted mainly of a uniform proliferation of elongated spindle cells arranged in a herring bone pattern, simulating fibrosarcoma. Focally there was a conventional embryonal pattern with scattered rhabdomyoblasts possessing an eosinophilic cytoplasm. Immunohistochemical studies disclosed expression of muscle markers such as desmin and muscle-specific actin, in both the embryonal and spindle-cell areas and myoglobin only in the embryonal areas. Such histological features are unusual for classical embryonal rhabdomyosarcoma. The anatomical site and age of the patient are also atypical.
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