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  • Title: Subtypes of early age onset alcoholism.
    Author: Mezzich A, Tarter R, Kirisci L, Clark D, Buckstein O, Martin C.
    Journal: Alcohol Clin Exp Res; 1993 Aug; 17(4):767-70. PubMed ID: 8214411.
    Abstract:
    Forty-three adolescents qualifying for a DSM-III-R diagnosis of alcohol abuse/dependence were classified according to the internalizing-externalizing behavior dimension. Two clusters were identified. The majority of subjects clustered into a group characterized by behavioral dyscontrol and hypophoria (history of suicide attempts) (cluster 2), whereas the other group was primarily featured by negative affect (cluster 1). Cluster 2 subjects demonstrated more severe alcohol and drug use-related problems, behavioral disturbances, and general psychopathology; lower prevalence of depressive disorders; and less severe anxiety disorders. These results, implicating two variants of adolescent alcohol abuse/dependence, suggest the need to tailor differential treatments to adolescents with alcohol abuse/dependence based on personality characteristics and clinical presentation.
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