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  • Title: [Isopycnic centrifugation in metrizanide gradient of ribosomal ribonucleoprotein precursor particles].
    Author: Auger MA, Longuet M.
    Journal: C R Acad Hebd Seances Acad Sci D; 1976 May 31; 282(21):1889-92. PubMed ID: 821661.
    Abstract:
    Metrizamide has been described as a new medium for isopycnic centrifugation of unfixed biological particles. In the murine leukemia cell line L 5178 Y, the buoyant density of 80 S and 60 S preribosomal particles was found to be 1,22 g/cm3, which is noticeably lighter than buoyant densities of mature ribosomal particles.
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