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  • Title: [Outcome of conservative treatment of high-degree vesicoureteral reflux].
    Author: Martínez Urrutia MJ, Muguerza R, Eire F, López Pereira P, Hasan A, Espinosa L, Jaureguizar E.
    Journal: Cir Pediatr; 1993 Jul; 6(3):105-7. PubMed ID: 8217502.
    Abstract:
    We performed a retrospective study to evaluate the results of a nonsurgical approach of primary high grade vesicoureteral reflux (VUR). 241 patients (209 III and 32 IV) were reviewed during and average time of 9.4 years. 55% of them were under 6 months and 52% had bilateral reflux (50% III and 63% IV). During the observation period spontaneous resolution of reflux was observed in 126 (60%) with grade III at 5 years and 26% in patient with grade IV at 4 years. In both grades the duration of persistent reflux was analyzed using life-table method. When age at presentation was compared with duration of reflux there was a shorter time of reflux in those patients presenting from age 0 to 6 months. New renal scars developed in 5 patients during the period of observational therapy. We conclude that high grade VUR can resolve over a protracted interval. On basis of this analysis, we advocate the surgical correction in these patients after 5-year period to grade III and 2-year to grade IV.
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