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  • Title: Serious childhood angiomas: unsuccessful alpha-2b interferon treatment. A report of four cases.
    Author: Teillac-Hamel D, De Prost Y, Bodemer C, Andry P, Enjolras O, Sebag G, Brunelle F, Hubert P, Nihoul-Fekete C.
    Journal: Br J Dermatol; 1993 Oct; 129(4):473-6. PubMed ID: 8217766.
    Abstract:
    Over a 4-year period, we managed four children with alarming haemangiomas (two cases of Kasabach-Merritt syndrome and two life-threatening haemangiomas). Systemic steroid therapy was ineffective. Other treatments (radiotherapy, anti-platelet drugs) were also ineffective in the Kasabach-Merritt patients. On the basis of recent reports on the effects of interferon on endothelial cells, we used alpha-2 interferon therapy, but obtained no response.
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