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  • Title: [Special MR methods for primary bone tumors: II. Volume selective 1H-spectroscopy].
    Author: Schick F, Duda S, Laniado M, Jung WI, Claussen CD, Lutz O.
    Journal: Rofo; 1993 Oct; 159(4):325-30. PubMed ID: 8219117.
    Abstract:
    The method of localised 1H MR spectroscopy was used in 19 examinations in 9 patients with primary bone tumours in order to obtain spectral signals and to determine whether these are specific for tumour classification. The spectra were obtained by a double spin echo method and the tumour tissue showed very high water content and only minor lipid and proton signals which showed J-coupling characteristics. The latter are not found in normal bone marrow and are probably due to products of tumour metabolism. The resolution of the spectra within a 13 mm or 20 mm tissue cube depends largely on the structural homogeneity of the tumour. The signal patterns in the spectra were not specific to histological tumour types.
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