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  • Title: Escherichia coli producing CNF1 and CNF2 cytotoxins in animals with different disorders.
    Author: Pohl P, Oswald E, Van Muylem K, Jacquemin E, Lintermans P, Mainil J.
    Journal: Vet Res; 1993; 24(4):311-5. PubMed ID: 8220498.
    Abstract:
    Two DNA probes were used for the detection of CNF1- and CNF2-positive E coli strains in a collection of 553 E coli isolates from cattle, sheep, goats, pigs, horses, dogs, cats and poultry. CNF-positive E coli were frequently associated with septicaemia in cattle, dogs, and cats, with diarrhoea in calves, cats and dogs, and with abortion in bovine and porcine species. CNF2-positive strains were observed among adult healthy cattle. They were also found in cases of pneumonia, metritis, mastitis in cattle and in 1 case of metritis of a mare. The physiopathology induced by CNF-positive E coli strains remains to be elucidated. However, the impact of CNF strains on veterinary pathology is clear and the diagnosis of CNF-producing E coli should become routine in veterinary practice.
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