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  • Title: Viscoelasticity of BLM from choline plasmalogen, alkylacyl- and diacyl-glycerophosphocholines.
    Author: Hianik T, Dlugopolský J, Masaryková D, Paltauf F, Hermetter A.
    Journal: Gen Physiol Biophys; 1993 Jun; 12(3):271-82. PubMed ID: 8224783.
    Abstract:
    Mechanical characteristics of bilayer lipid membranes (BLM) composed of alkenylacyl-, alkylacyl-, and diacyl-glycerophosphocholines were studied by measuring modulus of elasticity in the direction normal to BLM plane, E perpendicular, and coefficient of dynamic viscosity eta. Alkenylacyl-glycerophosphocholine (choline plasmalogen) BLM typically show larger values of E perpendicular and eta as compared to their analogs, suggesting a tighter packing of their hydrophobic regions. Increasing cholesterol concentrations are associated with monotonically increasing values of parameters E perpendicular and eta of plasmalogen BLM, whereas a nonmonotonic dependence of these parameters with a maximum around c = 66 mol% cholesterol is typical for the diacyl analog POPC. This may be due to the formation of cholesterol clusters at c > 66 mol%.
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