These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Cone-rod dystrophy in the Guinea baboon.
    Author: Vainisi SJ, Fishman GA, Wolf ED, Boese GK.
    Journal: Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol; 1976; 81(4 Pt 1):OP725-30. PubMed ID: 822562.
    Abstract:
    Three stages of macular degeneration associated with diffuse cone-rod dystrophy have been described in a Guinea baboon (P papio) colony. Clinically, the affected animals displayed abnormal behavior associated with decreased vision. Ophthalmoscopically, the lesion in the macula was the only change observable in early cases; retinal vessel attenuation and optic disc pallor were seen only in the advanced cases. The hyperfluorescence of the maculae was the result of loss of pigment in the pigmented epithelium. Electrophysiology supported a cone-rod sequence of this retinal dystrophy. Histologic examination confirmed the theory that the dystrophy began in the cone outer segment but eventually involved all the photoreceptors.
    [Abstract] [Full Text] [Related] [New Search]