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Title: Negative autoregulation by the Escherichia coli SoxS protein: a dampening mechanism for the soxRS redox stress response. Author: Nunoshiba T, Hidalgo E, Li Z, Demple B. Journal: J Bacteriol; 1993 Nov; 175(22):7492-4. PubMed ID: 8226698. Abstract: The soxRS redox stress regulon of Escherichia coli is triggered in two stages, with the activated SoxR protein stimulating the soxS gene, whose product then triggers transcription of approximately 10 promoters. Genetic and biochemical experiments presented here show that SoxS protein also limits soxS transcription in vivo and binds the soxS promoter in vitro.[Abstract] [Full Text] [Related] [New Search]