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  • Title: 99Tcm-DTPA for the measurement of glomerular filtration rate.
    Author: Hilson AJ, Mistry RD, Maisey MN.
    Journal: Br J Radiol; 1976 Sep; 49(585):794-6. PubMed ID: 822911.
    Abstract:
    Comparison of the blood clearances of 51Cr-EDTA and 99Tcm-Sn-DTPA, in a series of 45 patients with a wide range of glomerular filtration rates, showed that there was a good correlation between the estimates of G.F.R. obtained using the two chelates simultaneously. The single-injection, single-exponential method of G.F.R. estimation was used, with a correction factor of 0.964 for 99Tcm-DTPA, which gave a relationship of G.F.R.Cr = 2.3+G.F.R.Tcml/min with a correlation coefficient of 0.99. 99Tcm-DTPA is a suitable agent for the estimation of glomerular filtration rate.
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