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  • Title: Plasmodium falciparum proteinases and red blood cell invasion.
    Author: Schrével J, Barrault C, Deguercy A, Grellier P, Lawton P, Heidrich HG, Caballero M, Monsigny M, Mayer R.
    Journal: Parassitologia; 1993 Jul; 35 Suppl():103-5. PubMed ID: 8233598.
    Abstract:
    Malarial proteinases of the erythrocytic life-cycle are used to design new inhibitors capable of blocking the parasite's development. The Merozoite Proteinase for Erythrocytic Invasion (MPEI) of Plasmodium falciparum, a neutral proteinase, and the acidic Pf37 proteinase acting on spectrin as substrate, are good candidates for this kind of strategy.
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