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  • Title: [Cefuroxime axetil--efficiency and safety for treatment of upper airways and middle ear infections in children].
    Author: Barliński J.
    Journal: Pol Tyg Lek; ; 48(9-10):233-5. PubMed ID: 8234058.
    Abstract:
    The study aimed at assessing the clinical efficiency, safety, and tolerance of cefuroxime axetil suspension in the treatment of children with the acute upper respiratory infections and/or the acute otitis media. The trial was open, multicenter, involving 304 children aged between 3 months and 12 years. They were recruited from 18 general practice centers in Poland. Children were given cefuroxime axetil suspension in the dose of 10 mg/kg body weight (upper respiratory) or 15 mg/kg otitis media. max. 250 mg) bid. Children were examined prior to the treatment, 3-4 days following the start of therapy, 1-2 days after completion of the treatment, and followed-up for 14 days. Post-therapy examination has shown 93% cure rate. During the follow-up period 0.77% of patients relapsed. Only minor adverse reactions were reported by 4.9% of patients. Most common complaint was vomiting. Cefuroxime axetil suspension was safe and effective therapy in the acute upper respiratory infections and the acute otitis media in childhood.
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